Anti-inflammatory Lignans from the Fruits of Acanthopanax sessiliflorus

Anti-inflammatory Lignans from the Fruits of Acanthopanax sessiliflorus

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A new lignan, named acanthosessilin A (1), as well as eight known lignan and lignan glycosides 2-9 were isolated from VIT A GLYCOLIC TONER an ethanolic extract of Acanthopanax sessiliflorus fruits.The chemical structures were determined by spectroscopic methods, including HR-EIMS, 1D NMR (1H, 13C, DEPT), 2D NMR (gCOSY, gHSQC, gHMBC, NOESY), and IR spectroscopy.All isolated compounds were tested for the ability to inhibit LPS-induced nitric oxide production in In-Line Blower RAW264.7 macrophages.