Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells
Engagement of the Post-Natal Formulas B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated.Centrosome re-orientation to the immune synapse has emerged as a critical regulatory step to guide the local recruitment and secretion of lysosom